Differential roles for the Co2+/Ni2+transporting ATPases, CtpD and CtpJ, inMycobacterium tuberculosisvirulence
نویسندگان
چکیده
منابع مشابه
Fine-tuning of Substrate Affinity Leads to Alternative Roles of Mycobacterium tuberculosis Fe2+-ATPases.
Little is known about iron efflux transporters within bacterial systems. Recently, the participation of Bacillus subtilis PfeT, a P1B4-ATPase, in cytoplasmic Fe(2+) efflux has been proposed. We report here the distinct roles of mycobacterial P1B4-ATPases in the homeostasis of Co(2+) and Fe(2+) Mutation of Mycobacterium smegmatis ctpJ affects the homeostasis of both ions. Alternatively, an M. tu...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2013
ISSN: 0950-382X
DOI: 10.1111/mmi.12454